Periocular basal cell carcinoma in under 40’s – Is more aggressive treatment warranted?
نویسندگان
چکیده
منابع مشابه
DIFFERENTIATION BETWEEN MORPHOLOGICALLY AGGRESSIVE AND NON-AGGRESSIVE BASAL CELL CARCINOMA BY AgNOR STAINING
Argyrophilic staining of nucleolar organizer regions (AgNOR) has been considered to be useful in the diagnosis and prognostic evaluation of different cutaneous tumors. In order to evaluate the role of the AgNOR technique in discriminating aggressive from non-aggressive basal cell carcinoma (BCC), paraffin-embedded histologic sections from 30 cases of aggressive BCC (BCC2) and 30 cases of n...
متن کاملThe Study for Diagnostic Value of β-Catenin Immunohistochemistry Marker in Distinction of Aggressive and Non-Aggressive Basal Cell Carcinoma
Background & Objective: Basal cell carcinoma (BCC) is a common skin cancer arising from the basal layer of the epidermis and its appendages. They are locally invasive, aggressive, and destructive of skin and the surrounding structures. β-Catenin is a multifunctional protein located to the intracellular side of the cytoplasmic membrane coded by the CTNNB1 gene, which maps to chr...
متن کاملVismodegib for periocular and orbital basal cell carcinoma.
IMPORTANCE Basal cell carcinoma (BCC) represents 90% of malignant eyelid tumors and is locally invasive and destructive, if left untreated. OBJECTIVE To assess the feasibility of using vismodegib for periocular and orbital BCC based on its efficacy and tolerability. DESIGN, SETTING, AND PARTICIPANTS In this prospective observational case series, consecutive patients with periocular or orbit...
متن کاملANGIOGENESIS ASSESSMENT IN BASAL CELL CARCINOMA
Basal cell carcinoma (BCC) is currently the most common cutaneous cancer found in humans. Although it generally shows a relatively benign course (BCCl), some cases show aggressive behavior (BCC2). Until recently, traditional histologic diagnostic criteria have failed to discriminate unequivocally between BCC 1 and BCC2. In this study we selected 50 cases of BCC and categorized them into tw...
متن کاملImiquimod cream efficacy in the treatment of periocular nodular basal cell carcinoma: a non-randomized trial
BACKGROUND The recurrence rate of periocular nodular basal cell carcinoma (PNBCC) following treatment with imiquimod (IMQ) has not yet been established. Previous studies did not include histological follow-up. The aim of this analysis was to evaluate the efficacy of topical immunotherapy with 5% IMQ cream for the treatment of PNBCC. METHODS STUDY DESIGN A prospective, non-randomized, and u...
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ژورنال
عنوان ژورنال: Eye
سال: 2018
ISSN: 0950-222X,1476-5454
DOI: 10.1038/s41433-018-0290-1